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pubchem-mcp-server

pubchem-mcp-server is an MCP server, listed under databases. Its repository has 10 GitHub stars and is licensed under Apache-2.0; we last read it on 2026-10-22.

This software allows searching the PubChem chemical database for compounds, properties, safety data, bioactivity, cross-references, and entity summaries through MCP. It supports communication via STDIO or Streamable HTTP.

Install

Read from pubchem-mcp-server’s own README, close to verbatim -- not written by us, and not guessed.

npx @cyanheads/pubchem-mcp-server -y

What it reaches, and what it needs

Reaches
○ not recognised
Credential
○ none found

Maintenance

Stars
10
State
listed
Licence
Apache-2.0
From the repository

Search the PubChem chemical database for compounds, properties, safety data, bioactivity, cross-references, and entity summaries via MCP. STDIO or Streamable HTTP.

pubchem-mcp-server compared with similar servers

pubchem-mcp-server compared with the closest alternatives, by services reached, credentials, stars, last update and licence
ServerReachesNeedsStarsLast updateLicence
pubchem-mcp-server (this page)—None listed102026-10-17Apache-2.0
CodeGraphContextneo4jNEO4J_PASSWORD4,3602026-10-22MIT
dbhubmysql, postgres, sqliteNone listed3,7022026-10-21MIT
mcp-server-mysqlmysqlNone listed2,1732026-07-27MIT
mysql_mcp_servermysqlMYSQL_PASSWORD1,4022026-08-02MIT
servermysqlMYSQL_ROOT_PASSWORD8742025-08-09MIT

Ranked by services in common with pubchem-mcp-server, then by stars. Figures are from each repository when we last read it.

Common questions about pubchem-mcp-server

What does pubchem-mcp-server do?
This software allows searching the PubChem chemical database for compounds, properties, safety data, bioactivity, cross-references, and entity summaries through MCP. It supports communication via STDIO or Streamable HTTP.
How do I install pubchem-mcp-server?
Its own README gives this command: npx @cyanheads/pubchem-mcp-server -y. Run it where your MCP client can launch the server, and check the README for any settings it asks for.
Is pubchem-mcp-server official and is it maintained?
We found nothing naming it as a vendor’s official server. Its repository has 10 GitHub stars and its state in our directory is listed. Its last commit we recorded was on 2026-10-17.
What licence does pubchem-mcp-server use?
The repository declares the Apache-2.0 licence.

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